Prophylactic activity of engineered EcN against P. aeruginosa infection. (a) Scheme for pre colonization of EcN in the GI tract followed by P. aeruginosa infection. (b) Colonization of EcN was assessed by fecal counting of bacteria as a function of time in animals that received different numbers of cells by oral gavage. (c) The level of P. aeruginosa was tracked over six days after giving 1010 cfu of the pathogen to each group of pretreated mice. (d) Total viable P. aeruginosa cell counts from fecal samples at day six post-infection. The data from two independent experiments are shown (n=5–10). * P<0.01(one-way ANOVA with Bonferroni correction for multiple comparisons). Data are presented in box plots with median as center line, 10 and 90 percent confidence limits, and minimum and maximum values. Graphics from Nature Communications.
Date Taken: | 08.22.2017 |
Date Posted: | 08.22.2017 14:37 |
Photo ID: | 3695768 |
VIRIN: | 170822-A-AB123-003 |
Resolution: | 926x958 |
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