Space Telescope Imaging Spectrograph (STIS), the most versatile spectrograph ever to fly on Hubble, ceased operations in August 2004 due to failure of its power supply. In order to restore STIS to operational status, astronauts may attempt an on-orbit replacement of one electronics board inside one of its main electronics boxes. The Cosmic Origins Spectrograph (COS) that will be added during Servicing Mission 4, and STIS are highly complementary and would work effectively together to provide a full set of spectroscopic tools for astrophysical research. The STIS instrument's accomplishments include determining the atmospheric composition of an exoplanet as well as spectra and images at ultraviolet and visible wavelengths of the Universe from our solar system out to cosmological distances. Note: Animated sequence depicting the servicing of the Space Telescope Imaging Spectrograph during Hubble Space Telescope Servicing Mission 4. Animator: Bob Sauls (Frassanito and Associates). Producer: Michael D. McClare (HTSI).