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    ‘Hack-a-Vent’ Challenge Leads to Innovative, Low-Cost Ventilators

    ‘Hack-a-Vent’ Challenge Leads to Innovative, Low-Cost Ventilators

    Courtesy Photo | Lt. Col, Preston, Commander of the US Army Health Clinic in Hohenfels, inspects mobile...... read more read more

    UNITED STATES

    06.12.2020

    Story by Sarah Marshall 

    Uniformed Services University

    Amid the global pandemic, hospitals across the country have filled with patients suffering from respiratory distress due to COVID-19. To help keep up with a demand for ventilators, the Department of Defense (DoD) recently launched a collaborative effort across the services, along with the Uniformed Services University (USU), to harness innovation and potentially save lives.

    In March, using the U.S. Special Operations Command digital platform, Vulcan, the DoD put out a call for proposals to build domestically-sourced ventilators that would be easy to operate and would cost under $500 to produce. A week after the effort, referred to as the “Hack-a-Vent” challenge, was launched, 172 ventilator proposals were submitted.

    “Most of the proposals were truly innovative ventilators,” said Navy Cmdr. (Dr.) Arlene Hudson, chair of Anesthesiology at USU.

    Hudson led a team from USU and Walter Reed National Military Medical Center (WRNMMC) to assess and select the proposals submitted to Vulcan and test the prototypes in a USU lab, testing the ventilators’ ability to control ventilation. The clinical assessment team, made up of surgical, medical, and critical care experts, helped narrow the proposals to five finalists, based on criteria they developed for clinical usability and the most important features that would be required to support the most limited ventilation requirements. Their team also worked with a panel of engineers who tested the basic mechanics of the prototypes, ensuring the technology would be feasible. Five prototypes from organizations spanning large corporations, small businesses, universities and government engineering teams were selected for further development.

    Hudson noted the remarkably quick turnaround to garner and develop these prototypes, obtain the necessary research compliance approvals at USU to test them in the lab, and then thoroughly assess their clinical and engineering capabilities. Normally, this process would take years, but instead took only a few weeks due to the ability to leverage an existing large animal lab established for the Battlefield Shock Organ Support program to address this immediate national need.

    “It was really an impressive effort. It was really extraordinary,” Hudson said.

    Once they had the data to determine the prototypes could ventilate the appropriate animal model, the DoD’s Joint Acquisition Task Force, in collaboration with the Defense Health Agency, designated the Air Force and the Wright Brothers Institute in Dayton, Ohio, to rapidly lead the five final teams through the U.S. Department of Food and Drug Administration Emergency Use Authorization process. Now, the Air Force Life Cycle Management Center has collaborated with the ventilator development teams at USU and WRNMMC to prepare designs for mass production.

    The challenge and resulting development process would not have been a success if not for the incredible team effort, according to Hudson. The group included a number of USU faculty, including Army Col. (Dr.) Jessica Bunin, Army Lt. Col. (Dr.) Jacob Collen, Army Lt. Col. (Dr.) Christian Popa, Navy Cmdr. (Dr.) John Benjamin, and Navy Cmdr. (Dr.) Ashley Humphries.

    “The success of this effort is a testament to the university’s close ties with Walter Reed, and support from the university’s leadership,” Hudson added. “This could not have been done on a dime. It’s because of the support that already existed for military-relevant research that facilitated and allowed for us to turn this around so quickly. Thanks to this effort, we will fill a gap and potentially save lives.”

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    NEWS INFO

    Date Taken: 06.12.2020
    Date Posted: 06.12.2020 11:05
    Story ID: 372011
    Location: US

    Web Views: 95
    Downloads: 1

    PUBLIC DOMAIN